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γδT细胞在病毒免疫中的作用 被引量：1

Antiviral activity of γδT cells
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摘要 γδT细胞被视为天然免疫和获得性免疫之间的桥梁,与NK细胞、巨噬细胞及树突状细胞等免疫细胞共同构成机体抵抗病原微生物的第一道防线.γδT细胞可以通过释放如穿孔素、颗粒酶等细胞毒性分子,表达Fas-FasL诱导细胞凋亡以及分泌IFN-γ等方式发挥细胞免疫效应,也可以释放IL-2、IL-4、IL-5、IL-7、IL-22等细胞因子调节体液免疫.γδT细胞在抗感染、抗肿瘤及免疫耐受等病理生理中发挥着重要作用.本文就γδT细胞及其主要功能在抗病毒免疫中所扮演的作用作一综述.
作者 崔大伟 梁雨 陈瑜
机构地区 浙江大学医学院附属第一医院检验科
出处 《中华临床感染病杂志》 CAS 2013年第1期59-64,共6页 Chinese Journal of Clinical Infectious Diseases
关键词 T细胞 病毒 免疫
分类号 R3 [医药卫生—基础医学]
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共引文献30

同被引文献26

  • 1贺伟锋,谭江玲,罗高兴,陈希炜,尹芝南,吴军.γδ T细胞与CD4^+ T细胞产生IFN-γ动力学的比较研究[J].重庆医学,2006,35(22):2042-2044. 被引量：3
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中华临床感染病杂志
2013年 第1期

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