期刊文献+

慢性乙型肝炎患者肌酸激酶重度升高一例 被引量:1

Marked elevation of creatine kinase in chronic hepatitis B patient: report of one case
原文传递
导出
摘要 患者男,51岁,因'乙型肝炎表面抗原(HBsAg)阳性6年,肌酸激酶升高1个月余'于2011年6月22日入住广州市第八人民医院肝病科.患者曾在2005年体检时发现HBsAg阳性、转氨酶升高,定期于广州市第八人民医院门诊复诊并口服护肝降酶药物治疗,但转氨酶仍反复异常,查血清HBV DNA1.82×108 U/mL,遂于2008年3月起服用阿德福韦酯(10 mg/d)抗病毒治疗并按时规律服药.经治疗后于2008年12月9日开始定期检测HBV DNA,结果均低于检测下限(<500 U/mL).2011年5月发现血清肌酸激酶(CK)进行性升高(5月10日:1727 U/L,6月10日:2152 U/L,6月21日:2745 U/L).
出处 《中华临床感染病杂志》 CAS 2013年第4期248-249,共2页 Chinese Journal of Clinical Infectious Diseases
  • 相关文献

参考文献10

二级参考文献28

  • 1DIBISCEGLIE A,LAI CL,GANE E,et al. Telbivudine Clobe trial:maximal early HBV suppression is predicitive of optimal two-year efficacy in nucleoside-treated hepatient [J]. Hepatology, 2006,44:230A.
  • 2EMMET B,KEEFFE EB,DOUGLAS T,et al. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States [J]. Clin Gastroenterol Hepatol, 2008,6:1315-1341.
  • 3PINTI M,SALOMONI P,COSSARIZZA A. Anti-HIV drug and the mitochondria[J]. Biochim Biophys Acta,2006,1757: 700-703.
  • 4LAI CL,GANE E,LIAU YF,et al. Telbivudine versus lamivudine in patients with hepatitis B [J]. N Engl J Med, 2007,357:2576-2588.
  • 5Fontana RJ.Side effects of long-term oral antiviral therapy for hepatitis B.Hepatology,2009,49(S5):185-195.
  • 6Sánchez Hellín V,Gutiérrez Rodero F.Toxicogenetics of antiretroviral treatment:Neurotoxicity,hepatotoxicity,lactic acidosis,kidney damage,and other adverse effects of antiretroviral drugs.Enferm Infecc Microbiol Clin,2008,6:24-33.
  • 7Zhao S, Tang L, Fan X, et al. Comparison of the efficacy of lamivudine and telbivudinc in the treatment of chronic hepatitis B: a systematic review. Virol J, 2010, 7:211.
  • 8Liaw YF, Gane E, Leung N, et al. 2-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology, 2009, 136: 486-495.
  • 9Lai CL, Leung N, Teo EK, et al. A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B. Gastroenterology, 2005, 129: 528-536.
  • 10Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med, 2007, 357: 2576- 2588.

共引文献37

同被引文献15

  • 1Min HK,Kim EO,Lee SJ. Rifampin-associated tubulointersititial nephritis and Fanconi syndrome presenting as hypokalemic paralysis[J].{H}BMC Nephrology,2013.13.
  • 2Law ST,Li KK,Ho YY. Acquired fanconi syndrome associated with prolonged adefovir dipivoxil therapy in a chronic hepatitis B patient[J].{H}American Journal of Therapeutics,2013.e713-e716.
  • 3Gracey DM,Snelling P,McKenzie P. Tenofovir-associated Fanconi syndrome in patients with chronic hepatitis B monoinfection[J].{H}Antiviral Therapy,2013.
  • 4Kamran SC,Pendergraft WF,Harmon DC. Ifosfamide-induced Fanconi syndrome and desmopressin-responsive nephrogenic diabetes insipidus[J].{H}American Journal of Medicine,2013.e7-e8.
  • 5Girgis CM,Wang T,Ngu MC. Hypophosphataemic osteomalaeia in patients on adefovir dipivoxil[J].{H}Journal of Clinical Gastroenterology,2011.468-473.
  • 6Kahn J,Lagakos S,Wulfsohn M. Efficacy and safety of adefovir dipivoxil with antiretroviral therapy:a randomized controlled trial[J].{H}JAMA:the Journal of the American Medical Association,1999.2305-2312.
  • 7Izzedine H,Hulot JS,Launay-Vacher V. Renal safety of adefovir dipivoxil in patients with chronic hepatitis B:two double-blind,randomized,placebo-controlled studies[J].{H}Kidney International,2004.1153-1158.
  • 8Gara N,Zhao X,Collins MT. Renal tubular dysfunction during long-term adefovir or tenofovir therapy in chronic hepatitis B[J].{H}Alimentary Pharmacology and Therapeutics,2012.1317-1325.
  • 9Kim YJ,Cho HC,Sinn DH. Frequency and risk factors of renal impairment during long-term adefovir dipivoxil treatment in chronic hepatitis B patients[J].{H}Journal of Gastroenterology and Hepatology,2012.306-312.
  • 10Fontana RJ. Side effects of long-term oral antiviral therapy for hepatitis B[J].{H}HEPATOLOGY,2009.S185-S195.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部