老年尿路感染病原菌分布特点和耐药性分析

Analysis of the Distribution of Pathogens and Antimicrobial Resistance in Elder Patients with Urinary Tract Infection

目的分析老年人尿路感染的病原菌分布特点及对不同抗生素的耐药状况,为临床合理应用抗生素提供依据。方法回顾性分析过去3年中对134例老年尿路感染患者的中段尿培养及药物敏感性的实验资料。结果共检出病原菌123株,其中革兰阴性杆菌占79.7%,主要为大肠埃希菌(55.3%)、肺炎克雷伯菌(5.7%)、铜绿假单胞菌(4.1%),对亚胺培南、氨曲南、头孢吡肟耐药率低;革兰阳性球菌占18.7%,对万古霉素、克林霉素敏感;真菌占1.6%。结论老年人尿路感染病原菌耐药性严重,耐药监测对合理选择抗生素十分必要。

Objective To analyze the distribution and antimicrobial resistance of pathogens in elder patients with urinary tract infection,and to provide the evidence for clinic in using antibiotics.Methods Retrospective analysis was conducted on the data about the urine culture and drug sensitivity that were identified in 134 elder adult patients with urinary tract infection in the past 3 years.Results A total of 123 strains of pathogens were isolated.Gramnegative bacill accounted for 79.7%,escherichia coil 55.3%,klebsiella pneumonia 5.7%,pseudomonas aeruginosa 4.1%.The resistance rates to immipenam,aztreonam,cefepime were low.Grampositive cocci accounted for 18.7%,sensitive to vancomycin and clindamycin,and fungi 1.6%.Conclusion The antimicrobial resistance of pathogens was serious in elder adult patients with urinary tract infection.It is important to survey successively the pathogens and its antimicrobial resistance for clinic in the antinomycin selection.