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中国非酒精性脂肪性肝病诊疗指南(2010年修订版) 被引量:272

Guidelines for management of nonalcoholic fatty liver disease:an updated and revised edition
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摘要 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种与胰岛素抵抗(insulin resistance,IR)和遗传易感密切相关的代谢应激性肝脏损伤,其病理学改变与酒精性肝病(alcoholic liver disease,ALD)相似,但患者无过量饮酒史,疾病谱包括非酒精性单纯性脂肪肝(nonalcoholic simple fatty liver,NAFL)、非酒精性脂肪性肝炎(nonalcoholic steatohepatitis,NASH)及其相关肝硬化和肝细胞癌[1,2],NAFLD 是21世纪全球重要的公共健康问题之一,亦是我国愈来愈重视的慢性肝病问题[3]。
作者 范建高
出处 《中国医学前沿杂志(电子版)》 2012年第7期4-10,共7页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词 脂肪肝 诊断 治疗 指南[文献类型] 代谢综合征 Fatty liver Diagnosis/therapy Guidebooks[Publication type] Metabolic syndrome
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参考文献28

  • 1Farrell GC;Larter CZ.Nonalcoholic fatty liver disease:from steatosis to cirrhosis[J]Hepatology,2006(2 Suppl 1):S99-S112.
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二级参考文献21

  • 1项坤三.临床糖尿病本质认识的深化[J].中华糖尿病杂志,2009,1(1). 被引量:11
  • 2Henry V(o|¨)lzke,Daniel M.Robinson,Volker Kleine,Roland Deutscher,Wolfgang Hoffmann,Jan Lüdemann,Ulf Schminke,Christof Kessler,Ulrich John.Hepatic steatosis is associated with an increased risk of carotid atherosclerosis[J].World Journal of Gastroenterology,2005,11(12):1848-1853. 被引量:29
  • 3Taylor BC, Yuan JM, Shamliyan TA, et al. Clinical outcomes in adults with chronic hepatitis B in association with patient and viral characteristics: A systematic review of evidence. Hepatology, 2009, 49(5 Suppl): S85-95.
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  • 7Fan JG, Farrell GC. Epidemiology of non-alcoholic fatty liver disease in China. J Hepatol, 2009, 50: 204-210.
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  • 9Petta S, Camma C, Di Marco V, et al. Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection. Am J Gastroenterol, 2008, 103: 1136-1144.
  • 10Tsochatzis E, Papatheodoridis GV, Hadziyannis E, et al. Serum adipokine levels in chronic liver diseases: association of resistin levels with fibrosis severity. Scand J Gastroenterol, 2008, 43:1128-1136.

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