老年心房颤动患者临床危险因素分析

Analysetheriskfactorsof elderlypatients with atrialfibrillation

背景和目的心房颤动(房颤)是老年患者最常见的心律失常,老年房颤患者发生心力衰竭、血栓栓塞和死亡的危险性增加。本文分析老年房颤患者临床危险因素的特点,为临床防治提供依据。方法本院从2010年6月至2011年6月共668例房颤患者接受治疗,老年房颤患者308例(≥60岁),非老年房颤患者360例(<60岁)。回顾性分析两组患者的临床基线资料并进行比较。结果老年房颤患者的临床特征:与非老年房颤患者相比,女性房颤患者所占比例显著增高(P<0.001),合并高血压患者显著增高(P<0.01),合并左房前后径、左室射血分数、阵发性房颤患者所占比例和糖尿病患者所占比例无显著性差异(P>0.05),CHADS2评分显著增高(P<0.001)。结论老年房颤患者并发症较多,发生远期卒中、心力衰竭和全因死亡率的风险增加且预后较差。

Objectve Atrial fibrillation (AF) is the most common arrhythmia in elderly patients. The risk of heart failure, thromboembolism and death in elderly patients with atrial fibrillation increases. In this study we analysis the clinical characteristics of elderly patients with atrial fibrillation to provide the basis for clinical prevention and treatment. Methods The clinical data of 668 elderly patients with atrial fibrillation at the Anzhen Hospital from July 2010 to July 2011 were studied, elderly group including 308 cases (≥60 years) and non-elderly group including 360 cases (<60 years).The patients’ clinical baseline data were recorded and compared between the two groups. Results The clinical characteristics of elderly patients with atrial fibrillation: compared with non-elderly group, no significant difference in left atrial diameter, left ventricular ejection fraction, the proportion of patients with paroxysmal atrial fibrillation and patients with diabetes mellitus(P>0.05), the higher percentage of female patients (P<0.001)and patients with hypertension(P<0.01) in the elderly group, the higher percentage of patients with CHADS2 score≥2 in the elderly group(P<0.001). Conclusions The elderly patients with atrial fibrillation have more complications, more risk of heart failure, thromboembolism and death and poor prognosis.