富血小板血浆在颜面部脂肪移植中的应用

Application of Platelet Rich Plasma in Facial Fat Transplantation

目的:探讨自体脂肪颗粒结合自体富血小板血浆（PRP）注射移植颜面部的美容效果。方法：2009年10月至2012年5月，105例颜面肌肤衰老导致额、颞部凹陷、泪槽沟及鼻唇沟深陷患者，接受自体脂肪颗粒结合富血小板血浆注射移植，填充颜面部矫正凹陷畸形和皱纹，纯化后脂肪颗粒每20ml加配PRP 1～1.5ml比例为适宜。结果：本组病例手术后经3～8个月随访观察，颜面部凹陷得到矫正，皮肤润泽，细腻光滑，皱纹减少。结论：PRP富含多种生长因子，能促进细胞再生、血管化，减少移植的脂肪被吸收，自体脂肪颗粒结合PRP注射移植至面部，不仅大大提高颗粒脂肪成活率，而且该技术取材方便，治疗效果可靠，临床实用性强。

Objective To explore the clinical effect of platelet rich plasma(PRP)combined with self lipochondrion in facial fat transplantation. Methos From October 2009 to May 2012,105 patients who had forehead and temple sinking,and deep sunken of nasolabial groove caused by facial skin senility,received the transplantation of PRP combined with self lipochondrion. The sinking part and winkles of face were filled. The most suitable proportion was every 20ml purified lipochondrion added with 1~1.5ml PRP. Results After 3 to 8 month following up,excavation of face was corrected,with fine and smooth skin,and less winkles. Conclusion PRP has many growth factors,and it can promote cytothesis and vascularization,and reduce the assimilation of the transplanted fat. Self lipochondrion combined PRP can not only increase the survival rate of lipochondrion,but also the material of the operation is convenient,with reliable treatment efficacy and clinical practice.