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应用液质联用技术诊断两起河豚毒素食物中毒 被引量：2

Diagnosis of tetrodotoxin food poisoning in two cases by liquid chromatography-tandem mass spectrometry
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摘要 目的快速查明食物中毒的原因,为中毒事件的调查提供技术支持。方法通过现场流行病学调查分析中毒原因,运用液质联用方法对样品进行检测确证。结果两起食物中毒样品均检出河豚毒素。结论本方法检测快速、准确、结果可靠,为快速查明中毒原因和患者的临床救治提供可靠的诊断依据。 Objective To quickly investigate the cause of food poisoning and provide technical support for the incident.Methods The possible cause of poisoning was analyzed by field epidemiological investigation,and liquid chromatography-tandem mass spectrometry was further applied to confirm the accuracy.Results Tetrodotoxin was found in the samples of two cases of food poisoning.Conclusion This method is rapid,accurate,and reliable,and it provides a scientific evidence for identifying the cause of tetrodotoxin food poisoning cases and clinic treatment.
作者 岳亚军 张风雷 赖少阳 龙朝阳 游杰 夏伟 张律
机构地区 深圳市罗湖区疾病预防控制中心 广东省疾病预防控制中心
出处 《食品安全质量检测学报》 CAS 2013年第3期673-676,共4页 Journal of Food Safety and Quality
基金 深圳市罗湖区软科学研究项目(2010093)~~
关键词 河豚毒素 液质联用 食物中毒 tetrodotoxin liquid chromatography-tandem mass spectrometry(LC-MS/MS) food poisoning
分类号 R155.5 [医药卫生—营养与食品卫生学]
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参考文献10

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共引文献12

同被引文献23

  • 1李云峰,马晨晨.养殖河豚鱼毒素的研究[J].食品安全质量检测学报,2014,5(3):819-823. 被引量：6
  • 2杨晓东,邓峰,刘子文,梁春穗,邱建锋,肖俊豪.广东省常见河豚鱼含毒状况研究[J].广东卫生防疫,1997,23(4):4-8. 被引量：10
  • 3黄军,严美姣,陈国宏.河豚毒素的起源及其研究进展[J].生物技术通讯,2006,17(6):998-1000. 被引量：32
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二级引证文献6

食品安全质量检测学报
2013年 第3期

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