药用植物红茂草化学成分及抗炎作用研究进展

Research progress on chemical constituents and anti-inflammatory effects of medicinal plant Dicranostigma leptodum(Maxim.) Fedde

红茂草民间多用于治疗开放性淋巴结核和各类创伤性炎症,富含紫堇碱、异紫堇碱和异紫堇啡碱等多种异喹啉类生物碱。红茂草提取物具有抗菌、抑菌、抗溶血和改善微循环、提高机体免疫力、保护心肌和修复肝损伤等作用,并对各种结核病及炎症有显著疗效,其药用价值具有广阔的开发和应用前景,本文综述了红茂草主要化学成分及其生物活性,从抗菌、抗病毒、保肝、提高免疫细胞活性和细胞因子分泌、促进创伤和炎症愈合等方面归纳了红茂草的抗炎研究进展。

The Dicranostigma leptopodum (Maxim.) Fedde was used to treat the open tuberculosis of lymph node and all kinds of traumatic inflammation. It contains the effective components of alkaloids charac-tering as the corydine, isocorydine and d-isocorydine, and its extract has the effects of antibiosis, bacteriostasis, anti-hemolysis. It can improve microcirculation and enhance immunity function, myocardial protection and re-pair liver damage. In addition, it has significant curative effect for all kinds of tuberculosis and inflammation. This article sum up main chemical compositions and its biological activity about dicranostigma leptodum (maxim.) fedde, conclude anti-inflammatory research progress of dicranostigma leptodum (maxim.) fedde through the antibacterial, antiviral, protect liver, improve the activity of immune cells and cytokines secretion, promote healing of wounds and inflammation.