运动对腹部脂肪积累及肥胖基因表达的影响

Effects of Long-term Exercise on the Intrabdominal Visceral Fat Accumulationand the Obesity Gene Expression

复制了系统游泳运动减少腹部脂肪积累的大鼠模型;用Northern印记杂交测定了训练大鼠及对照大鼠ob mRNA表达量;并对运动减肥的分子生物学机制进行初步探讨。研究结果表明系统游泳运动减少腹部脂肪积累与运动所致的ob mRNA表达水平增高密切相关。

Some metabolic disorders induced by abdominal obesity have become the major risk factors for cardiovascular disease (CVD) and the prevention and cure of CVD by reducing body weight and fat has become one of the important tasks in medical and exercise physiological science. Practical studies reported that leptin. the product of obesity gene, could reduce body weight and fat. The purpose of this study is to investigate the effects of long -term swimming exercise on the intrabdominal visceral fat accumulation and on obesity mRNA expression level in white fat pads and to make primary study on the molecularbiological mechanism of body fat loss by exercise. Results showed that reduction of intrabdominal visceral fat accumulation by exercise was highly related to the high level of obesity mRNA after long -term swimming exercise.