摘要
目的 :观察利胆药物———郁金对兔离体胃平滑肌的影响 .方法 :取兔胃肌条 ,安置在各恒温灌流肌槽中并用BL 310生物技能实验系统记录胃各部平滑肌条的收缩活动 .结果 :郁金显著升高兔胃底和胃体纵行肌条张力 ,减小胃体收缩波平均振幅 ,并有剂量依赖关系 .结论 :郁金对胃肌条收缩活动具有明显的兴奋作用 ,这种兴奋作用部分经由胆碱能M受体介导 .
Objective:To study the effect of Yujin on contractile activity of isolated gastric muscle strips in rabbits. Methods:Longitudinal muscle strips of stomach from rabbits were taken. Each isolated muscle strip was put in a tissue chamber containing 5 mL krebs solution and motility of muscle strips was recorded simultaneously. Results:Yujin significantly raised the resting tension of longitudinal muscle (LM) strips of gastric fundus and body and decreased mean contractile amplitude of gastric body. The effect of Yujin on gastric contraction showed dose-effect relationship and could be eliminated by atropine partly. Conclusion:The results indicates that Yujin has significant exciting action on contractile activity of isolated gastric muscle strips in rabbits and the action of Yujin to stomach has direct relation with M receptor.
出处
《宁波大学学报（理工版）》
CAS
2004年第2期227-229,共3页
Journal of Ningbo University：Natural Science and Engineering Edition
关键词
胃平滑肌条
郁金
收缩活动
阿托品
消炎痛
六烃季胺
smooth muscle of Stomach
Yujin
contractile activity
Atropine
Indomethacin
Hexamethonium
