补充谷氨酰胺对运动员免疫系统功能的影响

Influence of Glutamine Supplement on Immune System Function of Athletes

以优秀赛艇运动员为研究对象 ,以外周血 T淋巴细胞亚群和血浆免疫球蛋白为免疫检测指标 ,观察了较长时间大负荷训练对运动员免疫功能的影响和长期低剂量补充 L-谷氨酰胺对消除机体免疫抑制的作用。结果显示 :口服补充谷氨酰胺使外周血抑制性 T淋巴细胞亚群减少 ,CD4 + / CD8+比值升高 ,提示通过口服补充谷氨酰胺可以减少长时间大负荷训练对机体免疫平衡的影响 ,减少机体免疫受抑程度 ,有助于维持机体正常的免疫平衡 ;口服补充谷氨酰胺可以提高运动员安静状态血清免疫球蛋白 M含量 (Ig M)

This paper takes elite boating athletes as research subjects,and peripheral subset of T lymphocyte and plasma immunoglobulin as indexes to examine the effect of oral glutamine supplement on function of immune system during long-term maximal training load,and to study possible effect of long-term low dose oral glutamine on diminishing the immune suppression.The result shows that the number of subset of suppressive T lymphocyte decreases and CD 4+/CD 8+ ratio increases significantly in glutamine group.It suggests that oral glutamine supplement may reduce the effect of long-term maximal training load on the balance of immune system,diminish the degree of immune suppression,helps to keep the normal balance of immune system.Oral glutamine supplement may increase the volume of resting serum immunoglobulin.