强化训练后血浆β—内啡呔及生长抑素与T淋巴细胞及其亚群的关系

Relationship Between Plasma P-endorphin and Somatostatin and T-lymphocyte and Its Subpopulations After Intensive Training

7名中长跑运动员经过4 周大运动量强化训练后,出现免疫功能抑制,CD_8^+T细胞比例明显升高,CD_4^+/CD_8^+比值下降,呈倒置现象。放射免疫测定的结果表明,4周强化训练后,运动员安静时血将β—内啡呔（β—EP）和生长抑素（SS）均明显升高,β—EP和SS对运动试验的反应性降低。结果提示,强化训练后,运动员机体的免疫功能抑制可能与神经内分泌调节紊乱有关。

The authors find that after 4 week's intensive training the immune disturbances of the seven middle and long distance runners were caused. Significant increase in absolute numbers of CD8 cells and decreased CD4/CD8 ratio were noted. The Results of radiodimmunoassay show that concentration of β 梕ndorphin and somatostatin in plasma at rest after four 梬eek intensive training are markedly ranged and that of (3梕ndorphin and somatostatin in plasma are not markely changed. The Results suggest that after the intensive training,the immunosuppression of the runners was induced,which may be caused by the disorder of the neuroendocrine secretion regulation.