摘要
目的:综述了以壳聚糖或其衍生物为基础的多种特殊靶向载体系统的研究现状。方法:以国内外近年有代表性的文献为依据,进行分析、整理和归纳。结果与结论:由于壳聚糖具有一些独特的物理和生物特性,并且通过修饰后增加了壳聚糖的一些性质,使其成为优良的药物载体,从而实现药物的靶向性。这一载体材料近年来逐渐受到重视,具有良好的开发和应用前景。
Objective: To provide an insight into various target-specific carriers,based on chitosan and its derivatives.Methods: This review is analyzed,collated and summarized by home and abroad recent years representative literature.Results and Conclusion: Chitosan is a good drug carriers because of it has some unique physical and biological characteristics and by adding some properties after being modification.This carrier is paid more attention in recent years,and have good development and application prospect.
出处
《黑龙江医药》
CAS
2013年第4期564-567,共4页
Heilongjiang Medicine journal
关键词
壳聚糖
纳米粒子
靶向
传递系统
chitosan
nanoparticles
targeted
delivery system.