丁香酚的药理学作用研究进展

Advance in Pharmacological Research of Eugenol

丁香酚是丁香油的主要成分,为一种有机酚。现代药理学研究表明其具有解热镇痛、抗炎、麻醉等药效;此外还具有抗细菌、抗真菌、抗氧化、抗癌、驱蚊避虫等多种活性,同时毒副作用小,代谢残留少,因而在医药、化妆品等诸多领域备受青睐。随着其功能团、作用位点、作用方式的进一步阐明以及有关数据库的建立,丁香酚的应用前景将更加广阔。对丁香酚的药理学作用研究进展进行了综述。

Eugenol,a main constituent of clove oil,is an organic phenol,and has antipyretic,analgesic,anti-inflammatory and anesthetic efficacy.In addition,pharmacological studies showed its anti-bacterial,anti-fungal,antioxidant,anticancer,insect repellent and other activity.It has small side effects,toxicity and non metabolism residue,so that it was widely accepted in many fields such as pharmaceuticals,cosmetics,etc.With further elucidation of its functional groups,sites of action and mode of action,and with the establishment of related database,eugenol will have wider use.This paper briefly reviewed pharmacological effects of eugenol.