霸王鞭化学成分的研究

Chemical Constituents from the Euphorbia antiquorum L.

采用硅胶柱色谱和高效液相色谱等分离方法对霸王鞭乙醇提取液正己烷萃取物化学成分进行分离纯化,得到了6个单体化合物。通过理化性质及波谱数据分析进行结构鉴定的结果,确定它们的结构分别为:大戟二烯醇(1)、大戟醇(2)、β-谷甾醇(3)、豆甾醇(4)、taraxetol(5)东莨菪素(6),其中,化合物1、2、5、6为首次从该植物中分离得到。

The chemical constituents of Euphorbia antiquorum L.were studied by the methods of column chromatography and HPLC.Six compounds were isolated from the ethanol extracts of Euphorbia antiquorum and the structures were elucidated on the basis of spectral analysis and physiochemical properties.They were identified as euphol(1),euphorbol(2),β-sitosterol(3),stigmasterol(4),taraxetol(5),and 6,7,8-trimethoxy coumarin(6).The compounds 1,2,5,and 6 were isolated from this plant for the first time.