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Chronic Liver Failure after Treatment with Infliximab for Ankylosing Spondylitis in a Patient with Hepatitis B

Chronic Liver Failure after Treatment with Infliximab for Ankylosing Spondylitis in a Patient with Hepatitis B
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摘要 A 50-year-old man with ankylosing spondylitis was treated successfully with infliximab,who was also a HBV carrier for about twenty-five years.After injection with infliximab for four times,he developed jaundice and HBV DNA was detectable in serum.Serum aminotransferase and total bilirubin levels were higher than normal.Then he was hospitalized and treated with entacavir and Chinese herb medicine.But his liver damage aggravated and was diagnosed as acute on chronic liver failure.Finally,liver transplantation was carried out and he was cured successfully. A 50-year-old man with ankylosing spondylitis was treated successfully with infliximab,who was also a HBV carrier for about twenty-five years.After injection with infliximab for four times,he developed jaundice and HBV DNA was detectable in serum.Serum aminotransferase and total bilirubin levels were higher than normal.Then he was hospitalized and treated with entacavir and Chinese herb medicine.But his liver damage aggravated and was diagnosed as acute on chronic liver failure.Finally,liver transplantation was carried out and he was cured successfully.
机构地区 Beijing Ditan Hospital
出处 《国际感染病学(电子版)》 CAS 2013年第2期84-87,共4页 Infection International(Electronic Edition)
关键词 Acute on chronic liver failure Hepatitis B Ankylosing spondylitis Acute on chronic liver failure Hepatitis B Ankylosing spondylitis
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