产前超声诊断双胎妊娠胎儿脑损伤的探讨

Prenatal Ultrasonographic diagnosis of cerebral injury in twin pregnancy

目的探讨双胎妊娠发生脑损伤的高危因素,为早期能宫内诊断双胎脑损伤提供帮助。方法分析报道2007～2009年经产前超声怀疑并诊断的胎儿脑损伤的双胎妊娠4例,分析其临床高危因素及超声声像图特征。结果 4例双胎胎儿脑损伤中2例为双胎之一死亡、1例双胎输血综合征、1例病变胎儿伴脑室内出血。超声声像图共同特征表现为侧脑室周围散在囊腔样病变,其中3例经MRI证实,1例出生后经超声证实。结论双胎之一死亡的存活胎儿及双胎输血综合征的供血儿易发生脑损伤,临床工作中对于有上述高危病史胎儿,超声检查需给予足够的重视。

Objective To explore the high risk factor of cerebral injury in twin pregnancy in order to improve the recognition of this disease.Methods Retrospectively reviewed the four cases of cerebral injury in twin pregnancy from 2007 to 2009.Analyzed the characteristics of clinical medical history and the ultrasound imaging.Results The four cases of cerebral injury in twin pregnancy were two cases of death of co-twin,one with twin-twin transfusion syndrome(TTTS),the other accompany with Intraventricular hemorrhage.The common ultrasound imaging characteristics were the scattered capsilar space arounded the lateral ventricles.Three cases of them were certified by MRI,another were by ultrasound after birth.Conclusion When the twins pregnancy with death of co-twin and TTTS,there are protenial risk in the cerebral of survival fetus.An increasing in the vigilance of prenatal ultrasonographic diagnostician in those.