胎儿脐带囊肿荟萃分析(附1例报告)

One case report of fetal death due to the umbilical cord cyst and the literature review

目的探讨胎儿脐带囊肿临床特点及其诊治。方法结合1979~2007年中文文献报道对该病进行回顾性分析。结果共收集到32例胎儿脐带囊肿病例,其中19例具有较为完整的临床资料。B超首次诊断孕周17~38周,平均29.6周;其中单发脐带囊肿13例,多发6例,囊肿位置近胎儿侧9例,近胎盘侧4例,位于脐带其他位置5例,位置未描述1例;大小2.0~12.0 cm,平均5.4 cm;单发囊肿不良妊娠结局4例(4/13),多发囊肿中不良妊娠结局4例(4/6)。结论脐带囊肿形成原因不详,可能与胎儿染色体异常、畸形有关。超声是良好的产前诊断方法,临床上需与脐带血肿、脐带静脉瘤样扩张等相鉴别。发现脐带囊肿应详细检查、定期随访,目前尚无有效的治疗方案。

ObjectiveTo discuss the clinical diagnosis and therapy for umbilical cord cyst in China. MethodsOne case was selected from the files of the Women's Hospital School of Medicine Zhejiang University.And others had been diagnosised and reported in China from 1979 to 2007 in Chinese literature.All were analyzed retrospectively.ResultsIn China 19 cases reported,The mean size of the cyst was 5.4 cm(range 2.0~12.0 cm),4 of 13 patients(4/13) were associated with poor pregnancy outcome(abnormality or stillbirth),when the umbilical cord cyst present single.Oppositely,4 of 6(4/6) multiple umbilical cord cysts were associated with poor pregnancy outcome.ConclusionsThe pathophysiological process of umbilical cord cyst is unclear,may be relating to the fetal abnormality or aneuploidy.The best way to diagnosis this illness is ultrasound,and the umbilical cord cyst should be differentiated to hematoma and umbilical vein varix.There was no standard treatment of this entity.we should take detail examination of the fetus and scan the cyst repeatly when the umbilical cord cyst was detected.