Anesthesia

209163 Changes in plasma colloid osmotic pressure during off-pump orthotopic liver transplantation/Zhang Xiaomei(Dept Anesthesiol,Tianjin 1st Centre Hosp,Tianjian 300192)…∥Chin J Anesthesiol.-2009,29(2).-151~153Objective To investigate the changes in plasma colloid osmotic pressure(COP)in patients undergoing off-pump orthotopic liver transplantation(OLT).Methods Thirty ASA Ⅱ-Ⅳ patients(liver function Child-Pugh grade B or C)aged 35-60 yr undergoing off-pump OLT were studied.Anesthesia was induced with midazolam,sufentanil,propofol and vecuronium and maintained with propofol infusion,isoflurane inhalation and intermittent iv boluses of sufentanil and vecuronium.Human albumin and fresh frozen plasma were infused during operation.Hemoglobin was maintained at 70-80 and 80-100 g/L during preanhepatic and anhepatic phase respectively.Urine output was maintained at 1,0.5 and 1-2 ml·kg-1·min-1 while CVP at 4-7,0-3 and 4-10 mm Hg respectively during preanhepatic,anhepatic and neo-hepatic phase.Blood samples were taken immediately before intravenous line was established (T0,baseline),at skin incision(T1),60 min of preanhepatic phase(T2)beginning of anhepatic phase(T3),30 min of anhepatic phase (T4),beginning of neohepatic phase(T5),30 min of neohepatic phase(T6) and the end of operation(T7)from internal jugular vein for determination of plasma COP,crystalloid osmotic pressure and serum albumin concentration.