Urethra,prostate

209268 Diagnostic value of perfusion weighted magnetic resonance imaging in prostate cancer and benign prostatic hyperplasia/Zhao Xin(Dept Radiol,Tianjin Med Univ Gen Hosp,Tianjin 300052)…∥Chin J Urol.-2009,30(3).-207~209Objective To evaluate the diagnosis and differential diagnostic value of perfusion weighted magnetic resonance imaging for prostate cancer(PCa)and benign prostatic hyperplasia(BPH).Methods Fifty-three cases were divided into 3 groups:group 1 including 23 cases of PCa,group 2 including 22 cases of BPH,and 8 healthy men enrolled in group 3 as normal control.The differences of perfusion related parameters(including rNEI,rMTE and rMSD)among the 3 groups were studied and analyzed.Results In peripheral zone,the value of rNEL in PCa patients was higher than that in BPH patients(t=11.64,P【0.001)and control healthy men(t=11.79,P【0.001).The value of rMTE of PCa patients was lower than that in BPH patients(t=3.50,P=0.002)and control(t=3.78,P=0.001).In central zone,the value of rNEI in PCa patients was higher than that in BPH patients(t=6.99,P【0.001)and control(t=10.32,P【0.001).According to ROC,the rNEI had the best differential diagnostic value.The optimal threshold was 6.44 with sensitivity of 91.3% and specificity of 81.8%for the PCa differentiation with BPH.Conclusion rNEI is and effective parameter to differentiate PCa from BPH.6 refs,2 tabs.