Effect of operation and different lipid emulsion on leukocyte chemiluminescence during operation in patients with gastrointestinal cancer

To observe the effect of operative trauma and lipid emulsion on leukocyte chemiluminescence (CL) during operation in patients with gastrointestinal cancer.Methods Twenty patients with advanced gastric cancer were divided into three groups:group 1,20% lipovenoes provided 30% nonprotein calories;group 2,20% lipofudingroup provided 30% nonprotein calories;group 3:glucose provided 100% nonprotein calories.Each group received full feeding with 25 kcal/kg every day,N 0.12 g/kg every day and were administered intravenously over 16～24 h as “all in one”.Preoperation,postoperation and after nutrition,the CL was determined.Results There was no significant difference in LC before and after operation.The LC in group 1 and group 2 was more brightened than that in group 3 4 days after TPN,but there was no significant difference in LC between group 1 and group 2.Conclusion (1) The operation trauma on the patients with gastric cancer has no significant effect on the LC.(2) TPN with lipid emulsion supplying 30% nonprotein calories can increase CL in patients with gastric cancer postoperation.5 refs,2 figs.