摘要
目的探讨上皮性卵巢癌患者术前PLT计数增高的临床意义。方法选择临床明确诊断的上皮性卵巢癌患者93例(卵巢癌组)、卵巢良性疾病患者40例(卵巢良性疾病组)及健康体检者40例(健康对照组)。取患者术前晨起空腹静脉血检测血小板(PLT)计数及血清CA125水平,结合临床资料进行统计分析。结果卵巢癌组PLT计数为277.6±96.2(×109/L),PLT计数升高47例(41.8%),均明显高于卵巢良性疾病组和健康对照组,差异有统计学意义(P<0.05)。晚期上皮性卵巢癌患者PLT计数明显高于早期患者(P<0.005)。淋巴结转移的晚期上皮性卵巢癌患者PLT计数显著高于无淋巴结转移者(P<0.005)。晚期上皮性卵巢癌患者PLT计数与血清CA125水平具有正相关性,(r=0.540,P<0.01)有统计学意义。结论 PLT计数增高可作为判断术前上皮性卵巢癌患者不良预后的指标之一。
Aim To investigate the clinical value of higher platelete in preoperative patients with epithilial ovarian cancer.Methods The study included the ovarian cancer group(n=93),benign ovarian diseases group(n=40) and healthy control group(n=40).The platelete and serum CA125 were measured in the study groups.The data would be analyzed combing with the clinical information.Results The platelete count was higher in ovarian diseases group((277.6±96.2)×109/L) than in benign ovarian diseases group and healthy control group,there was significance statisitical difference(P<0.05).The platelete count was higher in late-ovarian patients than that in pre-ovarian patients.The platelete count was higher in late-ovarian patients with lymphonodus metastasis than that without lymphonodus metastasis patients.The platelete count was correlation to the serum CA125(r=0.54,P<0.01).Conclusion The higher platelete count may be a prognostic marker in the patients with epithilial ovarian cancer.
出处
《临床检验杂志(电子版)》
2013年第2期343-344,339,共3页
Clinical Laboratory Journal(Electronic Edition)
关键词
上皮性卵巢癌
血小板计数
转移
epithelia l ovarian carc inom a
platelet count
Metastasis