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Rationale,design and baseline patient characteristics of the optimal type 2 diabetes management including benchmarking and standard treatment study in Greece

Rationale,design and baseline patient characteristics of the optimal type 2 diabetes management including benchmarking and standard treatment study in Greece
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摘要 AIM:To describe baseline data of the optimal type2 diabetes management including benchmarking and standard treatment(OPTIMISE)study in Greece.METHODS:"Benchmarking"is the process of receiving feedback comparing one’s performance with that of others.The OPTIMISE(NCT00681850)study is a multinational,multicenter study assessing,at a primary care level,whether using"benchmarking"can help to improve the quality of patient care,compared with a set of guideline-based reference values("non-benchmarking").In the Greek region,797 outpatients(457men,mean age 63.8 years)with type 2 diabetes were enrolled by 84 office-based physicians.Baseline characteristics of this population are presented.RESULTS:Hypertension was the most prevalent concomitant disorder(77.3%)and coronary heart disease was the most frequent macrovascular complication of diabetes(23.8%).Most patients were overweight or obese(body mass index 29.6±5 kg/m2),exhibiting mostly abdominal obesity(waist circumference102.6±13.6 cm).Biguanides were the most prevalent prescribed drugs for the management of diabetes(70.1%of all prescriptions),whereas statins(93.5%of all prescriptions)and angiotensin receptor blockers(55.8%of all prescriptions)were the most prevalent prescribed drugs for hyperlipidemia and hypertension,respectively.Only 37.4%of patients were on aspirin.Despite treatment,pre-defined targets for fasting plasma glucose(<110 mg/dL),glycated hemoglobin(<7%),systolic blood pressure(<130 mmHg and<125mmHg for patients with proteinuria)and low density lipoprotein cholesterol levels(<100 mg/dL and<70mg/dL for patients with coronary heart disease)were reached in a relatively small proportion of patients(29%,53%,27%and 31%,respectively).In a Greek population with type 2 diabetes,the control of glycemia or concomitant disorders which increase cardiovascular risk remains poor.CONCLUSION:Despite relevant treatment,there is a poor control of diabetes,hypertension and hyperlipidemia in Greek outpatients with type 2 diabetes. AIM:To describe baseline data of the optimal type2 diabetes management including benchmarking and standard treatment(OPTIMISE)study in Greece.METHODS:"Benchmarking"is the process of receiving feedback comparing one’s performance with that of others.The OPTIMISE(NCT00681850)study is a multinational,multicenter study assessing,at a primary care level,whether using"benchmarking"can help to improve the quality of patient care,compared with a set of guideline-based reference values("non-benchmarking").In the Greek region,797 outpatients(457men,mean age 63.8 years)with type 2 diabetes were enrolled by 84 office-based physicians.Baseline characteristics of this population are presented.RESULTS:Hypertension was the most prevalent concomitant disorder(77.3%)and coronary heart disease was the most frequent macrovascular complication of diabetes(23.8%).Most patients were overweight or obese(body mass index 29.6±5 kg/m2),exhibiting mostly abdominal obesity(waist circumference102.6±13.6 cm).Biguanides were the most prevalent prescribed drugs for the management of diabetes(70.1%of all prescriptions),whereas statins(93.5%of all prescriptions)and angiotensin receptor blockers(55.8%of all prescriptions)were the most prevalent prescribed drugs for hyperlipidemia and hypertension,respectively.Only 37.4%of patients were on aspirin.Despite treatment,pre-defined targets for fasting plasma glucose(&lt;110 mg/dL),glycated hemoglobin(&lt;7%),systolic blood pressure(&lt;130 mmHg and&lt;125mmHg for patients with proteinuria)and low density lipoprotein cholesterol levels(&lt;100 mg/dL and&lt;70mg/dL for patients with coronary heart disease)were reached in a relatively small proportion of patients(29%,53%,27%and 31%,respectively).In a Greek population with type 2 diabetes,the control of glycemia or concomitant disorders which increase cardiovascular risk remains poor.CONCLUSION:Despite relevant treatment,there is a poor control of diabetes,hypertension and hyperlipidemia in Greek outpatients with type 2 diabetes.
出处 《World Journal of Diabetes》 SCIE CAS 2014年第1期76-83,共8页 世界糖尿病杂志(英文版)(电子版)
基金 Supported by AstraZeneca
关键词 Diabetes BENCHMARKING TREATMENT tar-get Glycemic control DYSLIPIDEMIA Blood pressure Diabetes Benchmarking Treatment target Glycemic control Dyslipidemia Blood pressure
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