改善口服难溶性药物生物利用度的方法

Progress on improving the oral bioavailability of poorly water soluble drugs

目的总结提高难溶性药物生物利用度的方法,为难溶性药物制剂的研究提供参考。方法通过查阅近年来国内外关于生物利用度研究的文献26篇,对提高生物利用度的方法进行归纳和总结。结果有许多方法可以用来改善难溶性药物的生物利用度。结论选择一个合适的方法可以有效地提高药物的生物利用度。

Objective To summarize the methods of improving the oral bioavailability of poorly water soluble drugs and provide references to the development of the preparations thereof.Methods Retrieve and analyze the latest related 26 literatures,then generalize the methods to increase the bioavailability.Results Many methods can be used to improve oral bioavailability of poorly water soluble drugs.Conclusion The oral bioavailability of poorly water soluble drugs can be effectively enhanced by a suitable method.