摘要
Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say（Diptera: Culicidae）（Cx.Quinquefasciatus） to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh,India.Methods:Insecticide susceptibility assays were performed on wild-caught adult female Cx.quinquefasciatus mosquitoes to deltamethrin（0.05%）,cyfluthrin（0.15%）,permethrin（0.75%）,lambdacyhalothrin （0.05%）,malathion（5.0%） and DDT（4.0%）,the discriminating doses recommended by the World Health Organisation（WHO）.Results:The data showed that Cx.quinquefasciatus is highly resistant to DDT and malathion;the mortality was 28.33%and 27.5%,respectively and incipient resistance to synthetic pyrethroids（deltamethrin,cyfluthrin,permethrin,and lambdacyhalothrin）, where mortality ranged from 95.83%in permethrin to 98.33%in cyfluthrin and lambdacyhalothrin. Knockdown times(KDT<sub>50</sub>) in response to synthetic pyrethroids varied significantly between different insecticides（P【0.01） from 31.480 min for permethrin to 21.650 for cyfluthrin. Conclusions:The results presents here provide the status report of the insecticide resistance/ susceptibility of Cx.quinquefasciatus in major filaria endemic areas of northern India.
Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say(Diptera: Culicidae)(Cx.Quinquefasciatus) to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh,India.Methods:Insecticide susceptibility assays were performed on wild-caught adult female Cx.quinquefasciatus mosquitoes to deltamethrin(0.05%),cyfluthrin(0.15%),permethrin(0.75%),lambdacyhalothrin (0.05%),malathion(5.0%) and DDT(4.0%),the discriminating doses recommended by the World Health Organisation(WHO).Results:The data showed that Cx.quinquefasciatus is highly resistant to DDT and malathion;the mortality was 28.33%and 27.5%,respectively and incipient resistance to synthetic pyrethroids(deltamethrin,cyfluthrin,permethrin,and lambdacyhalothrin), where mortality ranged from 95.83%in permethrin to 98.33%in cyfluthrin and lambdacyhalothrin. Knockdown times(KDT_(50)) in response to synthetic pyrethroids varied significantly between different insecticides(P<0.01) from 31.480 min for permethrin to 21.650 for cyfluthrin. Conclusions:The results presents here provide the status report of the insecticide resistance/ susceptibility of Cx.quinquefasciatus in major filaria endemic areas of northern India.
