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The high incidence of acute hemolysis due to favism in Ahvaz,Iranclinical features and laboratory findings 被引量:1

The high incidence of acute hemolysis due to favism in Ahvaz,Iranclinical features and laboratory findings
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摘要 Objective:To collect comprehensive information about the features of favic patients in Ahvaz (Capital of Khouzestan,Iran) and analyze the extent of the differences with their corresponding in other regions.Methods:A total of 103 patients with acute hemolysis admitted to pediatric division of Abouzar Hospital located in the city of Ahvaz,Iran during 21st of June 2008 to 20th of June 2009 were analyzed retrospectively.Results:95.14% of the patients had favism while 4.86% of them underwent hemolysis due to other reasons.These patients were male(68.93%) and female children(31.06%) admitted mostly during the spring season.The three main symptoms were urine discoloration,jaundice and vomiting.At the admission time,the main hematologic findings were as follows:G6PD sufficient status(45.63%),G6PD deficient status(54.36%) and hemoglobin concentration:2.5-11.8(mean±SD:6.45±2.12) g/dL.Conclusions:In conclusion,Ahvaz was determined as a black zone for favism in which the disease can be considered a life threatening health problem.Moreover,slight differences were observed in the three main symptoms compared with favic patients in other regions. Objective:To collect comprehensive information about the features of favic patients in Ahvaz (Capital of Khouzestan,Iran) and analyze the extent of the differences with their corresponding in other regions.Methods:A total of 103 patients with acute hemolysis admitted to pediatric division of Abouzar Hospital located in the city of Ahvaz,Iran during 21st of June 2008 to 20th of June 2009 were analyzed retrospectively.Results:95.14% of the patients had favism while 4.86% of them underwent hemolysis due to other reasons.These patients were male(68.93%) and female children(31.06%) admitted mostly during the spring season.The three main symptoms were urine discoloration,jaundice and vomiting.At the admission time,the main hematologic findings were as follows:G6PD sufficient status(45.63%),G6PD deficient status(54.36%) and hemoglobin concentration:2.5-11.8(mean±SD:6.45±2.12) g/dL.Conclusions:In conclusion,Ahvaz was determined as a black zone for favism in which the disease can be considered a life threatening health problem.Moreover,slight differences were observed in the three main symptoms compared with favic patients in other regions.
出处 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2010年第5期399-401,共3页 亚太热带医药杂志(英文版)
关键词 Favism Glucose-6-phosphate DEHYDROGENASE DEFICIENCY Ahvaz Clinical features HEMOLYTIC ANEMIA Favism Glucose-6-phosphate dehydrogenase Deficiency Ahvaz Clinical features Hemolytic anemia
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参考文献15

  • 1Vichai Laosombat,Benjamas Sattayasevana,Teerachit Chotsampancharoen,Malai Wongchanchailert.Glucose-6-Phosphate Dehydrogenase Variants Associated with Favism in Thai Children[J]. International Journal of Hematology . 2006 (2)
  • 2T Meloni,G Forteleoni,A Dore,S Cutillo.Favism and hemolytic anemia in glucose-6-phosphate dehydrogenase-deficient subjects in North Sardinia. Acta Haematologica . 1983
  • 3G Donoso,H Hedayant,H Khayation.Favism, with special reference to Iran. Bulletin of the World Health Organization . 1969
  • 4CA Kattamis,A Chaidas,S Chaidas.G6PD deficiency and favism in the island of Rhodes (Greece). Journal of Medical Genetics . 1969
  • 5CA Kattamis,M Kyriazokou,S Chaidas.Favism: clinical and biochemical data. Journal of Medical Genetics . 1969
  • 6HK Lau,CH Li,AC Lee.Acute massive haemolysis in children with glucose-6-phosphate dehydrogenase deficiency. Hong Kong Medical Journal . 2006
  • 7MA Belsey.The epidemiology of favism. Bulletin of the World Health Organization . 1973
  • 8Scriver CR,Beaudet AL,Sly WS,Valle D.Glucose-6-phosphate dehydrogenase deficiency. The metabolic and molecular bases of inherited disease . 1995
  • 9K (o|¨)k AN,Ertekin MV,Ertekin V,Avci B.Henna (Lawsonia inermis Linn.) induced haemolytic anaemia in siblings. International Journal of Clinical Practice . 2004
  • 10Luzzatto L,poggi V.Glucose-6-phosphate dehydrogenase deficiency. Nathan and Oski’’s hematology of infancy and childhood . 2009

同被引文献27

  • 1S.M. Castro,R. Weber,U. Matte,G.J. Reclos,K.A. Pass,T. Tanyalcin,R. Giugliani.The use of LR values to check the best fit of cut-off values in G6PD deficient cases[J]. Clinical Biochemistry . 2007 (7)
  • 2MKaplan,HJVreman,CHammerman,CLeiter,BRudensky,MGMacDonald,DKStevenson.Combination of ABO blood group incompatibility and glucose‐6‐phosphate dehydrogenase deficiency: effect on hemolysis and neonatal hyperbilirubinemia[J]. Acta P?diatrica . 2007 (4)
  • 3Vinod K. Bhutani,Lois Johnson.Kernicterus in Late Preterm Infants Cared for as Term Healthy Infants[J]. Seminars in Perinatology . 2006 (2)
  • 4Elena Samilchuk,Ibrahim Al-Suliman,Esien Usanga,Sadika Al Awadi.Glucose-6-phosphate dehydrogenase (G6PD) mutations and UDP-glucuronosyltransferase promoter polymorphism among G6PD deficient Kuwaitis[J]. Blood Cells, Molecules and Diseases . 2003 (2)
  • 5Yi-Hao Weng,Yi-Hung Chou,Rey-In Lien.Hyperbilirubinemia in healthy neonates with glucose-6-phosphate dehydrogenase deficiency[J]. Early Human Development . 2003 (2)
  • 6Michael Kaplan,Cathy Hammerman.Glucose-6-phosphate dehydrogenase deficiency: a potential source of severe neonatal hyperbilirubinaemia and kernicterus[J]. Seminars in Neonatology . 2002 (2)
  • 7John D. Bancroft,Bill Kreamer,Glenn R. Gourley.Gilbert syndrome accelerates development of neonatal jaundice[J]. The Journal of Pediatrics . 1998 (4)
  • 8Michael Kaplan,Paul Renbaum,Ephrat Levy-Lahad,Cathy Hammerman,Amnon Lahad,Ernest Beutler.Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal?hyperbilirubinemia. Proceedings of the National Academy of Sciences of the United States of America . 1997
  • 9Kaplan M,Muraca M,Hammerman C,Vilei M T,Leiter C,Rudensky B,Rubaltelli F F.Bilirubin conjugation, reflected by conjugated bilirubin fractions, in glucose-6-phosphate dehydrogenase-deficient neonates: a determining factor in the pathogenesis of hyperbilirubinemia. Pediatrics . 1998
  • 10Compri Mariane B.,Saad Sara T. O.,Ramalho Antonio Sérgio.Investiga??o genético-epidemiológica e molecular da deficiência de G-6-PD em uma comunidade brasileira. Cadernos de Saúde Pública . 2000

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