摘要
Objective:To evaluate the in vitro inhibitory potential of commonly available antibiotic(discs) and paediatric suspensions against bacterial species from polio-positive faecal specimens.Methods:Commonly available antibiotic (discs) and oral,paediatric suspensions were screened for in vitro inhibitory activities against bacterial species from infantile polio-positive faecal specimens,using agar disc-diffusion and modified agar well-diffusion methods.Results:Isolated bacteria were Bacillus cereus,B.subtilis,Staphylococcus aureus,Streptococcus pneumoniae,Aeromonas hydrophila,Citrobacter aerogenes,Escherichia coli,Enterobacter aerogenes,Klebsiella pneumoniae,Pseudomonas aeruginosa,Proteus mirabilis,Pr.vulgaris,Shigella dysenteriae,Sh.flexneri,Sh. sonnei and Vibrio parahaemolyticus.Overall phenotypic antibiotic susceptibility rates among Gram-positive bacterial species were between 33.3%(augmentin) and 75.0%(chloramphenicol,erythromycin and gentamicin); higher susceptibility rates(48.6%-100.0%) were recorded among Gram-negative bacterial species, while between7.8%/ 10.1%(metronidazole / ampicillin) and 25.2%/28.1%(cotrimoxazole / septrin) were recorded towards paediatric antibiotics.Conclusions:Bacterial species from polio-positive fecal specimens are minimally susceptible to commonly available oral paediatric antibiotic suspensions in Nigeria.
Objective:To evaluate the in vitro inhibitory potential of commonly available antibiotic(discs) and paediatric suspensions against bacterial species from polio-positive faecal specimens.Methods:Commonly available antibiotic (discs) and oral,paediatric suspensions were screened for in vitro inhibitory activities against bacterial species from infantile polio-positive faecal specimens,using agar disc-diffusion and modified agar well-diffusion methods.Results:Isolated bacteria were Bacillus cereus,B.subtilis,Staphylococcus aureus,Streptococcus pneumoniae,Aeromonas hydrophila,Citrobacter aerogenes,Escherichia coli,Enterobacter aerogenes,Klebsiella pneumoniae,Pseudomonas aeruginosa,Proteus mirabilis,Pr.vulgaris,Shigella dysenteriae,Sh.flexneri,Sh. sonnei and Vibrio parahaemolyticus.Overall phenotypic antibiotic susceptibility rates among Gram-positive bacterial species were between 33.3%(augmentin) and 75.0%(chloramphenicol,erythromycin and gentamicin); higher susceptibility rates(48.6%-100.0%) were recorded among Gram-negative bacterial species, while between7.8%/ 10.1%(metronidazole / ampicillin) and 25.2%/28.1%(cotrimoxazole / septrin) were recorded towards paediatric antibiotics.Conclusions:Bacterial species from polio-positive fecal specimens are minimally susceptible to commonly available oral paediatric antibiotic suspensions in Nigeria.
