摘要
High level infant mortality rates and onset of drug resistance has led into the possible development of indigenous probiotics as alternative bacteriotherapy in the control of infantile bacterial diarrhoea.This study was to determine the in vitro inhibitory potential of four probiotic candidates obtained from Nigerian indigenous fermented foods and beverages and from faecal specimens of healthy infants on infantile Gram-positive diarrhogenic bacterial pathogens.Potential probiotic candidates,AAOOL4,L.reuteri AAOOCH1,L.plantarum AA0025NN and L.delbrueckii AAOOT20 were assayed for in vitro bactericidal effects on diarrhogenic bacterial test strains-Bacillus cereus 25S,B.cereus 32S,B.licheniformis 26S and B.licheniformis 39S.All the test strains inoculated into an industrial infant weaning food already seeded with the probiotic strains were significantly inhibited within 96 hours.L.acidophilus AAOOL4,L.reuteri AAOOCH1,L.plantarum AAOO25NN and L.delbrueckii AAOOT20 had in vitro bactericidal effects on bacteri isolates implicated in infantile diarrhoea,indicating the probiotic potential of the candidates.
High level infant mortality rates and onset of drug resistance has led into the possible development of indigenous probiotics as alternative bacteriotherapy in the control of infantile bacterial diarrhoea.This study was to determine the in vitro inhibitory potential of four probiotic candidates obtained from Nigerian indigenous fermented foods and beverages and from faecal specimens of healthy infants on infantile Gram-positive diarrhogenic bacterial pathogens.Potential probiotic candidates,AAOOL4,L.reuteri AAOOCH1,L.plantarum AA0025NN and L.delbrueckii AAOOT20 were assayed for in vitro bactericidal effects on diarrhogenic bacterial test strains-Bacillus cereus 25S,B.cereus 32S,B.licheniformis 26S and B.licheniformis 39S.All the test strains inoculated into an industrial infant weaning food already seeded with the probiotic strains were significantly inhibited within 96 hours.L.acidophilus AAOOL4,L.reuteri AAOOCH1,L.plantarum AAOO25NN and L.delbrueckii AAOOT20 had in vitro bactericidal effects on bacteri isolates implicated in infantile diarrhoea,indicating the probiotic potential of the candidates.
