Analysis of glistenings in hydrophobic acrylic intraocular lenses on visual performance

AIM:To assess patients’ visual performance with glistenings in one piece soft hydrophobic acrylic intraocular lenses(IOLs)(Alcon)2y postoperatively.METHODS:This cross section trial included 120 eyes with one piece IOL at 2y postoperatively.Glistening was classified in 4 groups,ranging from 0(none)to 3(most evident)according to their severity in IOLs optics observed under a slit lamp.All eyes underwent a uncorrected and best-corrected visual acuity evaluation(UCVA and BCVA,LogMAR scale),a complete clinical examination,a contrast sensitivity(CS)evaluation by F.A.C.T chart,and a visual field test by Humphrey Field AnalyzerⅡ(HFA).One-way ANOVA was used for quantitative data,while Pearsonχ2test was used for qualitative data to analyze the visual function of 4glistening groups.RESULTS:Totally 120 eyes were enrolled with 30 eyes in each glistening group.There was no statistical correlation between glistening grades and patients’age,IOLs power,postoperative UCVA and BCVA(P】0.05).Quantificationally,CS values among each group were not statistically different.However,qualitative analysis showed there were more eyes in grade 3 group than in grade 0 group having abnormally declined CS at high spatial frequency(10%vs 36.7%at 18 cpd,P=0.029;6.7%vs 26.7%at 12 cpd,P=0.013).Mean deviation(MD)of the visual field test was-2.14±2.31,-1.97±2.23,-3.02±3.17,-4.12±3.38 in group 0 to 3 respectively.There was a significant decrease in the most serious glistenings group(P=0.018).CONCLUSION:Glistenings may potentially have an impact on contrast sensitivity at high spatial frequency and MD in visual field test.

AIM:To assess patients’ visual performance with glistenings in one piece soft hydrophobic acrylic intraocular lenses(IOLs)(Alcon)2y postoperatively.METHODS:This cross section trial included 120 eyes with one piece IOL at 2y postoperatively.Glistening was classified in 4 groups,ranging from 0(none)to 3(most evident)according to their severity in IOLs optics observed under a slit lamp.All eyes underwent a uncorrected and best-corrected visual acuity evaluation(UCVA and BCVA,LogMAR scale),a complete clinical examination,a contrast sensitivity(CS)evaluation by F.A.C.T chart,and a visual field test by Humphrey Field AnalyzerⅡ(HFA).One-way ANOVA was used for quantitative data,while Pearsonχ2test was used for qualitative data to analyze the visual function of 4glistening groups.RESULTS:Totally 120 eyes were enrolled with 30 eyes in each glistening group.There was no statistical correlation between glistening grades and patients’age,IOLs power,postoperative UCVA and BCVA(P>0.05).Quantificationally,CS values among each group were not statistically different.However,qualitative analysis showed there were more eyes in grade 3 group than in grade 0 group having abnormally declined CS at high spatial frequency(10%vs 36.7%at 18 cpd,P=0.029;6.7%vs 26.7%at 12 cpd,P=0.013).Mean deviation(MD)of the visual field test was-2.14±2.31,-1.97±2.23,-3.02±3.17,-4.12±3.38 in group 0 to 3 respectively.There was a significant decrease in the most serious glistenings group(P=0.018).CONCLUSION:Glistenings may potentially have an impact on contrast sensitivity at high spatial frequency and MD in visual field test.