麦角酰胺对家兔行为和背侧海马神经元活动的影响

THE EFFECTS OF LSD ON THE BEHAVIOR AND ACTIVITY OF NEURONS IN THE DORSAL HIPPOCAMPUS NUCLELEUS IN RABBITS

实验观察了静脉或中脑中缝微量注射麦角酰胺(LSD)对清醒活动家兔行为和背侧海马神经元放电的影响。结果表明,LSD对家兔的行为,特别是舐嘴和转体活动有规律性的影响,两种行为变化的峰值始终有一间隔。静脉或中脑中缝核群注射LSD均可调制部分背侧海马神经元的活动,表现为放电频率的增加以及放电型式的改变。

the experiment was on the effects of extremely small intravenousinjection or injection of medbrain raphe of LSD on the behavior andfiring of the neurons in the dorsal hippocampus nucleus in the conscious,unanesthetized and unrestrained rabbits. The results show regular effectson the behavior,especially on the licking and turning activities.Therewas an interval in the peak of two behavioral changes from beginningto end. Intravenous injection or injection of medbrain raphe of LSDmay partially regulate the activity of neurons in the dorsal hippocamp-us, as was shown in the increase in the firing. frequency.and the changein the form of firing.