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激光用光导纤维导入大鼠皮层额叶和尾状核对纹状体的单胺类和氨基酸类神经介质含量的影响

THE EFFECTS OF LASER GUIDED BY OPTIC FIBER INTO FRONTAL CORTEX AND NUCLEI CAUDATE ON THE TRANSMITTERS OF MONOAMI NES AND AMINOACIDS IN THE CORPUS STRIATUM OF RATS
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摘要 迄今为止,激光在脑研究和临床应用上,主要是利用高功率激光做为手术刀、激光武器及其防护等方面。即使在这方面、由于激光辐照的穿透力很小,限制了它的应用。 The article studied the changes in transmitters of monoamines andaminoacids in the brain corpus striatum of 52 rats under laser radiation guidedby optic fiber into the brain. The results are as follows: 1) He-Ne laser radiation (6328A, 0.04mw) lasting 3 minutes causessignificant decrease of 5-HT, 5-HIAA and increase of GABA. Besides, laserradiation to the cortex leads to significant increase of ASP and GA, laserradiation to nuclei caudate decreases DA and GA. 2) Nitrogen ultraviolet laser radiation (3371A 0.04mJ/pulse, 10 pulses/sec) causes significant increase of 5-HIAA, GABA, ASP and decrease of 5-HT. Besides, laser radiation to cortex decreases NE, but radiation to nucleicaudate causes decrease of DA. 3) Both He-Ne laser and nitrogen ultraviolet laser radiation to mixedstandard sample in vitro causes photolysis of ASP. Besides, nitrogen laser alsocauses the photolysis of NE and DA. The effects of laser radiation to thebrain on 7 kinds of transmitters in the corpus striatum does not mean a simplephoto-chemical process, but they are complicated effects on brain metabolismprocesses.
机构地区 北京大学心理系
出处 《心理学报》 1982年第2期253-258,共6页 Acta Psychologica Sinica
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