双单体分子印迹光子晶体凝胶膜检测双酚A

Detection of Bisphenol A with The Double Monomer Molecularly Imprinted Photonic Crystal Hydrogel

采用光子晶体技术和分子印迹技术结合的方法,以双酚A为模板分子、甲醇为溶剂、甲基丙烯酸和丙烯酰胺为单体、乙二醇二甲基丙烯酸甲酯为交联剂、2,2-二乙氧基苯乙酮为光引发剂,制备了具有三维有序排列大孔结构的双酚A分子印迹光子晶体凝胶膜。随着双酚A的含量从10-10mol/L增加到10-3mol/L,布拉格衍射波长红移达36 nm,肉眼可分辨出颜色变化,且波长的变化不受离子强度和阿魏酸、水杨酸、对苯二酚等测定样品结构类似的干扰化合物的影响。

The molecularly imprinted photonic hydrogels (MIPH), based on the combination of photonic crystal and molecular imprinting technique, was prepared with Bisphenol A as template molecules, methanol as solvent, methacrylate and acrylamide as double functional monomer, ethy-lene glycol dimethyl methacrylate as cross-linked, 2, 2-diethoxyacetophenone as photoinitiator. When the molecular imprint photonic crystal film is soaked in bisphenol A buffer solution, peak wavelengths of Bragg diffraction will red-shift 36 nm with the concentration increasing from 10-10 mol/L to 10-3 mol/L. The color changes can be distinguished by bare eye. More importantly, the color changing is not influenced by the ionic strength and other structure analogue molecules like ferulic acid, salicylic acid and hydroquinol.