高血压患者的眼球后动脉血流动力学的特点

Retrobulbar arterial hemodynamic in patients with hypertension

目的:采用多普勒超声技术观察高血压患者的眼球后动脉血流动力学的特点。方法:选取2010年10月至2013年10月在本院就诊61例原发性高血压患者分5组,高血压低危组、中危组、高危组、很高危组共122只眼及19例健康者(对照组)38只眼,用彩色多普勒超声检查5组受检者的眼球后动脉(视网膜中央动脉(CRA)、睫状后动脉(SPCA))的血流动力学参数。结果:与对照组比较,高血压各组患者眼球后动脉(视网膜中央动脉(CRA)、睫状后动脉(SPCA))血流速度[包括收缩期峰值流速(PSV)、舒张末期流速(EDV)]均数之间的差异具有统计学意义(P<0.05),而阻力指数(RI)均数之间的差异,部分差异具有统计学意义。高血压低、中、高、很高危各组之间收缩期峰值流速(PSV)的两两比较,舒张末期流速(EDV)的两两比较,阻力指数(RI)的两两比较,均数之间的差异无统计学意义,P>0.05。结论:视网膜中央动脉、睫状后动脉的收缩期峰值流速、舒张末期流速的改变在高血压初期是比较敏感的指标。

Objective:To determine the hemodynamic characteristics of retrobulbar arteries in patients with essential hypertension by using Doppler ultrasonography.Methods:By using color Doppler ultrasonography,we measured the hemodynamic parameters of the retrobulbar arteries(i.e.central retinal artery(CRA) and posterior ciliary artery(SPCA)) in 61 patients(122 eye balls) with essential hypertension(further divided into low-,medium-,high- and very high-risk subgroups) and 19 healthy subjects(38 eye balls) who were recruited from Guangzhou Twelfth People' s Hospital and Guangdong Hospital of Traditional Chinese Medicine,between October2010 and 2013.Results:Compared with the control group,patients with essential hypertension demonstrated a different level of blood flow in the retrobulbar arteries,including CRA and SPCA,in terms of systolic peak velocity(PSV) end-diastolic velocity(EDV)(all P<0.05).Some subgroups yielded statistically significant differences in the resistance index(RI).No notable differences were found when comparing the PSV,EDV and RI among different subgroups in patients with essential hypertension(all P>0.05).Conclusion:The PSV and EDV of the CRA and SPCA are sensitive markers of essential hypertension.