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以人群为基础的吸烟与肺癌死亡关系的病例对照研究 被引量:6

The relationship between smoking and lung cancer deaths: a population based case control study
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摘要 目的 了解天津市人群肺癌死亡特征及吸烟等危险因素分布,为肺癌的预防控制提供依据.方法 采用2011年天津市疾病预防控制中心收集的天津市居民全死因监测数据,以所有肺癌死亡患者作为病例组(5746例),以所有非肺癌死亡患者作为对照组(59 625例),疾病分类采用《疾病和有关健康问题的国际统计分类》(ICD-10),采用SPSS 11.5软件进行单因素和多因素logistic回归分析.结果 天津市人群肺癌粗死亡率为58.00/10万,标化死亡率为31.52/10万,肺癌为所有恶性肿瘤死亡中的首位死因(38.25%,5746/15 023),男性肺癌死亡率高于女性(分别为66.91/10万,48.99/10万;x2=14.98,P=0.000).单因素非条件logistic回归分析结果显示:男性(Wald x2=6.09,P=0.014)、年龄增加(Wald x2=755.19,P=0.000)、已婚状态(Wald x2=348.24,P=0.000)、文化程度越低(Wald x2=326.21,P=0.000)、城市地区(Wald x2=291.08,P=0.000)、现在吸烟或已戒烟(Wald x2=1388.41,P=0.000)、每日吸烟支数多(Wald x2=289.43,P=0.000)、吸烟年限长(Wald x2=185.07,P=0.000)是肺癌死亡可能的危险因素.多因素非条件logistic回归分析结果显示,现在和既往吸烟(Wald x2=5.37,P=0.021;β=0.11;OR=1.12;95%CI=1.02~1.23)、每天吸烟支数多(Wald x2=90.24,P=0.000;β=0.34;OR=1.41;95%CI=1.31~1.51)和吸烟年限长(Wald x2=175.21,P=0.000;β=0.32;OR=1.38;95%CI=1.32~1.45)是肺癌死亡的独立危险因素;已婚状态(Wald x2=89.42,P=0.000;β=0.22;OR=0.80;95%CI=0.77~0.84)、女性(Wald x2=189.36,P=0.000;β=0.68;OR=1.98;95%CI=1.80~2.19)、城市地区(Wald x2=70.61,P=0.000;β=0.40;OR=0.67;95%CI=0.61~0.74)、文化程度低(Wald x2=42.40,P=0.000;β=0.19;OR=1.21;95%CI=1.14~1.28)是肺癌死亡的独立危险因素.结论 肺癌已成为危害天津市居民死亡的主要恶性肿瘤,吸烟与肺癌死亡密切相关,有必要开展控烟立法、开展肺癌危险因素知识健康教育,降低肺癌死亡危险.
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出处 《结核病与肺部健康杂志》 2012年第2期-,共6页 Journal of Tuberculosis and Lung Health
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参考文献21

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