期刊文献+

葡萄膜炎的病因及治疗进展 被引量:20

Progress in the etiology and treatment of uveitis
原文传递
导出
摘要 葡萄膜富含色素和血管,有营养眼球的作用,且血流缓慢,许多全身病可通过血流影响葡萄膜而使其致病。有时葡萄膜色素既是抗原又是靶细胞,因此葡萄膜炎是常见的严重眼病,种类繁多,病因相当复杂,治疗不当可导致患者失明,在致盲眼病中占有重要地位,致盲率为1.1%~9.2%,已引起世界范围内的重视。由于目前该类疾病发病及复发机制尚不完全清楚,故其预防无从着手,治疗效果也很不理想。因此寻求合理而有效的治疗药物,已成为眼科领域里一个亟待解决的问题。本文就葡萄膜炎的病因和治疗进展进行综述。 Uvea is rich in pigment and vessel with slow blood flow.It nourishes the eye ball, but many systemic diseases could influence uvea via blood flow as well.At the same time, uveal pigment could be both antigen and target cell at some point,so uveitis is common,serious,complex and will cause blindness without proper treatment.The rate of blindness induced by uveitis is as high as 1.1%-9.2% which has attracted worldwide attention.Since the pathogenesis and the recurrence mechanism has not been completely understood, neither good preventive method nor ideal treatment has been found and it has become an urgent problem in ophthalmology.The progress in etiology and treatment of uveitis will be reviewed in this paper.
作者 刘雪霞
出处 《中华眼科医学杂志(电子版)》 2014年第1期39-42,共4页 Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
关键词 葡萄膜炎 病因 治疗 综述 Uveitis Etiology Treatment Review
  • 相关文献

参考文献27

  • 1刘家琦;李凤鸣.实用眼科学[M]北京:人民卫生出版社,20108.
  • 2杨培增,王红,张震,钟华红,俞琼,傅涛,周红颜,黄祥坤.强直性脊椎炎伴发葡萄膜炎的临床特征和治疗[J].中华眼科杂志,2005,41(6):515-518. 被引量:23
  • 3Kelley WN. Tertbook of Rheumab[M].Saunders,2001.18-24.
  • 4蒋明;余得恩;林孝义.风湿病学[M]北京:科学技术出版社,20041038-1050.
  • 5Martin TM,Smith JR,Rosenbaum JR. Anlerir ureitis:current concepts of pathogenesis and interaction with the spondy loarthropathies[J].Cuur Opin Rheumatol,2002.337-341.
  • 6杨培增.葡萄膜炎诊断与治疗[M]北京:人民卫生出版社,2009510-535.
  • 7何守志.临床眼科学[M]天津:天津科学技术出版社,20025.
  • 8Aranda A,MayorgaC,Ariza A. IgE-mediated hy persensitivity reactions to methylprednisolone[J].ALLERGY,2010.1376-1380.
  • 9Czock D,Keller F,Rasche FM. Pharmacokinetics and pharmacodyamics of system:cally administered glucocorticoids[J].Clinical Pharmacokinetics,2005.61-98.
  • 10Habot-wilner Z,Sallam A,Roufas A. Pericular corticosteroid injection in the mana of aveitis in children[J].ACTA OPHTHALMOLOGICA,2010.299-304.

二级参考文献48

  • 1Gangaputra S,Ncwcomb CW,Liesegang TL,et al.Methotrexate for ocular inflammatory diseases.Ophthalmology,2009,116:2188-2198.
  • 2Miserocchi E,Baltatzis S,Ekong A,et al.Efficacy and safety of chlorambucil in intractablenoninfectiousuveitis.Ophthalmology,2002,109:137-142.
  • 3Zaghetto JM,Yamamoto MM,Souza MB,et al.Chlorambucil and cyclosporine A in Brazilian patients with Behcet's disease uveitis:a retrospective study.Arq Bras Oftalmol,2010,73:40-46.
  • 4Pujari SS,Kempen JH,Newcomb CW,et al.Cyclophosphamide for ocular inflammatory diseases.Ophthalmology,2010,117:356-365.
  • 5Roy M.Early clinical experience with leflunomide in uveitis.Can J Ophthalmol.2007,42:634.
  • 6Sobaci G,Erdem U,Durukan AH,et al.Safety and effectiveness of interferon alpha-2a in treatment of patients with Behcet's uveitis refractory to conventional treatments.Ophthalmology,2010,117:1430-1435.
  • 7Yamada Y,Sugita S,Tanaka H,et al.Comparison of infliximab versus ciclosporin during the initial 6-month treatment period in Behcet disease.Br J Ophthalmol,2010,94:284-288.
  • 8Goldstein DA.Uncovcring the risks of immunosuppressive therapy in patients with uveitis.Arch Ophthalmol,2010,127:799-800.
  • 9Okada AA.The dream of biologics in uveitis.Arch Ophthalmol,2010,128:632-635.
  • 10Jabs DA,Rosenbaum JT,Foster CS,et al.Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disordcrs:recommendations of an expert panel.Am J Ophthalmol,2000,130:492 513.

共引文献55

同被引文献312

引证文献20

二级引证文献62

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部