彩超与钼靶对乳腺导管内癌诊断的对比研究

Comparative Study on Color Doppler Ultrasonography and Digital Mammography in Diagnosis of Breast Ductal Carcinoma

目的探讨彩超(CDUS)与数字化钼靶摄影(钼靶)对乳腺导管内癌(DCIS)的诊断价值。方法回顾性分析73例患者79个病灶经病理确诊的DCIS术前CDUS及钼靶的影像资料,比较两者单独及联合诊断DCIS的价值。结果经病理证实79个病灶中48个为DCIS。CDUS及钼靶诊断DCIS的敏感度分别为66.67%(32/48)和70.83%(34/48),两者间差异无统计学意义(P>0.05),特异性分别为90.32%和80.65%,阳性预测值分别为91.43%和85.00%,阴性预测值分别为63.64%和64.10%;两者联合诊断的敏感度为95.83%(46/48),分别与其中一种诊断方法比较,差异有统计学意义(P<0.05)。结论 CDUS对DCIS病灶内部结构及周边导管结构紊乱检出优于钼靶,而钼靶能够较敏感地显示DCIS病灶内的微小钙化。两者联合可提高诊断DCIS的准确率。

Objective To investigate the value of color doppler ultrasonography(CDUS) and digital mammography in diagnosis of breast ductal carcinoma. Methods CDUS and digital mammography results of 73 nidi from 73 patients diagnosed as DCIS by postoperative pathological results were retrospectively analyzed. The value of CDUS, digital mammography, separately and the combination in the diagnosis of DCIS were compared. Results Forty-eight nidi were diagnosed as DCIS. The sensitivity of CDUS and digital mammography was 66.67%(32/48) and 70.83%(34/48) respectively, there was no statistical signifi cance(P>0.05), and the specifi city was 90.32% and 80.65 % respectively, the positive predictive value was 91.43% and 85.00% respectively and the negative predictive value was 63.64% and 64.10% respectively. The sensitivity of the combination was 95.83%(46/48). The difference between the combination and CDUS or digital mammography alone had statistical signifi cance(P<0.05). Conclusion CDUS has higher detection rate in internal structure and peripheral duct disorder but lower detection rate in microcalcifi cation of DCIS than digital mammography. The combination could improve the accuracy of DCIS diagnosis.