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阿尔茨海默病治疗靶点研究新进展 被引量:1

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摘要 阿尔茨海默病(AD)发病和遗传及环境因素有关,其大脑海马和新皮层乙酰胆碱转移酶(ChAT)水平显著减少,近年来不断发现AD发病和很多综合因素如β淀粉样蛋白(Aβ)沉积、磷酸化tau蛋白、脑内重金属及谷氨酸毒性作用等有关,其作为新的治疗靶点为开发新的治疗药物提供了新思路。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第6期1724-1726,共3页 Chinese Journal of Gerontology
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