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老年冠心病患者心血管事件的危险因素与药物治疗效果 被引量:20

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摘要 目的分析老年冠心病患者出现心血管事件的危险因素以及药物干预的效果。方法选取342例初诊冠心病的老年患者为研究对象,随访3年,60例患者失访或死亡,将随访期间出现心血管事件的患者纳入观察组,未出现心血管事件纳入对照组,单因素及Logistic多因素回归分析老年冠心病患者出现心血管事件的危险因素。根据患者的治疗依从性分为治疗依从组和非依从组,比较性别,年龄,文化程度,付费方式对治疗依从性的影响。结果①两组患者在年龄超过70岁,合并高血压,合并糖尿病,LDL-C升高,吸烟,纤维蛋白原升高,治疗完全依从比例方面存在显著差异(P<0.05);Logistic回归分析提示年龄≥70岁,LDL升高,糖尿病,高血压、纤维蛋白原升高是独立危险因素(P<0.05),治疗完全依从是保护因素;与性别、HDL-C水平无关。②随访期间观察组、对照组中分别有9例、31例患者能够完全依从治疗。经Logistic回归分析,年龄、付费方式与依从性呈负相关,文化程度与依从性呈正相关。结论年龄≥70岁,LDL升高,糖尿病,高血压、纤维蛋白原升高可增加老年冠心病患者发生心血管不良事件危险性,治疗完全依从是保护因素,自费、年龄≥70岁的患者治疗依从性较差,而高文化层次患者依从性较好。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第4期882-884,共3页 Chinese Journal of Gerontology
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二级参考文献56

共引文献47

同被引文献144

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