摘要
目的:促进本院临床合理应用抗生素。方法:收集本院2008年至2011年上报国家药品不良反应监测中心的145例抗生素药品不良反应(ADR)报告表进行统计分析。结果:其中以青霉素类56例(38.62%)占首位,其次为头孢菌素类和喹诺酮类,以静脉给药引起的不良反应最多101例(69.66%),在145例ADR中,60岁以上40例(27.56%),临床表现以皮肤系统的各种皮疹为最多。结论:抗生素发生ADR与给药途径、年龄等多种因素有关,临床医生应合理使用抗生素,减少ADR的发生。
[Objective] To understand the characteristics of adverse reactions of antibiotics and promote reasonable application of antibiotics.[Method] 145 cases of antibiotic ADR report that were reported to the National Adverse Drug Reaction Monitoring Center from 2008 to 2011 are analyzed.[Result] The adverse reaction to Perimycin of 56 cases(38.62%) topped the list,followed by cephalosporins and quinolones.The adverse reactions caused by intravenous injection up to 101 cases accounted for 69.66%.Among 145 cases of ADR,more than 40 patients are above 60 years old(27.56%)and variety of skin rashes in the skin system is the most ordinary clinical manifestations.[Conclusion] ADR to antibiotics is related to patients' age and other factors.Clinicians should use antibiotics rationally to reduce the occurrence of the ADR.
出处
《浙江医学教育》
2012年第5期61-63,共3页
Zhejiang Medical Education
关键词
抗生素
药品不良反应
合理使用抗生素
antibiotics
adverse drug reaction
rational use of antibiotics