变应性皮肤血管炎56例临床分析

The Clinical Analysis of 56 Cases of Allergic Cutaneous Vasculitis

目的探讨变应性皮肤血管炎患者的临床表现,实验室检查和治疗的特点,从而提高变应性皮肤血管炎的诊治水平。方法回顾性分析56例变应性皮肤血管炎患者的门诊和住院临床资料。结果56例患者均有不同程度的皮肤损害,18例有肾脏损害,15例出现关节炎症状,8例累及胃肠道,5例有肺部损害。除特发性和合并其他结缔组织病及肿瘤外,感染和药物只是血管炎的诱发因素,不是直接因素。结论变应性皮肤血管炎是累及皮肤和内脏器官的细小血管,特别是毛细血管后静脉的坏死性血管炎,临床上常有多形性皮损。治疗上应常规用糖皮质激素,并进行综合性治疗,控制感染,中药活血化瘀,清热利湿,可有显著疗效。

Objective To investigate the clinical manifestation,laboratory inspection and treatment of the patients with allergic cutaneous vasculitis. To raise the level of diagnosis and treatment. Methods The clinical data of 56 patients with allergic cutaneous vasculitis were analyzed retrospectively.Results 56 cases all had various skin lesions,18 cases had liver damage,15 cases had arthritis symptoms,8 cases had affected gastro-intestinal tract,5 cases had lung damage. Infection and medicine were the most common trigger factors. Conclusions Allergic cutaneous vasculitis affects small blood vesses of skin and visceral organs,especially capillary. Clinically it shows various skin lesions. The regular treatment is using corticosteroids,and also combine with other methods,such as controlling infection and traditional Chinese medicine. All have significant effect.