腹水超滤浓缩回输治疗78例顽固性腹水

Clinical observation on 78 patients with refractory ascites treated by ultrafiltration of ascites and perioneal reinfusion

目的探讨腹水超滤浓缩回输治疗顽固性腹水的疗效及影响因素。方法采用WLPHY-500型伟力电脑腹水超滤浓缩回输系统,YT-100型聚丙烯腈中空纤维滤过器,多头腹带、输血皮条等,按无菌操作规范将腹水引入透析器,超滤浓缩后回输至患者腹腔或静脉。结果腹水超滤浓缩回输治疗后患者体重、腹围显著降低,尿量增多;检测发现总蛋白和白蛋白水平较治疗前显著性提高(P<0.05),总胆红素(TBil)和丙氨酸氨基转移酶(ALT)无明显变化;血及腹水中电解质均无变化;腹水补体C3含量提高,内毒素水平下降。结论腹水超滤浓缩腹腔回输治疗各种顽固性腹水是有效的,不良反应少、适应证广、疗效快、操作简单,值得推广。

Objective To investigate the therapeutic effect on refractory ascities through ultrafiltration of ascities and peritoneal reinfusion.Methods Using WLPHY-500 machine of ultrafilter condensation and importantion,YT-100 hollow fiber dialyzer,the multi-thread belly-band,the transfusion rawhide,etc.The ascites was reinfused to the patients' abdominal cavity or vein according to sterile operating norms.Results After the treating end,the average weight and abdomen circumference were decreased,the urine output was increased,the clinical symptom was ameliorated.The level of the serum total protein and albumin were slightly arisen(P < 0.05),TBil and ALT were the same,the electrolyte concentration of blood and ascites were not changed(P > 0.05),C3 increased and endotoxin decreased.Conclusions Ascities ultrafiltration and concentration reinfusion takes an effect on refractory ascities with the characteristics of fewer side effects,simple,wider indications,faster effect,simple operation,therefore it is worth promoting.