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阿尔茨海默病患者淡漠综合征的综合评定 被引量:3

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摘要 目的:综合评定阿尔茨海默病(AD)患者淡漠综合征。方法:采用简易精神状态检查量表(MMSE)、神经精神调查表淡漠分量表(NPI-apathy)、淡漠评价评定量表临床版(AES-C)、里尔淡漠评定量表院护版(LARS-I)、老年抑郁量表(GDS)、陪护负担量表(CBS)等对轻中重度AD 83例评定。结果:AD患者淡漠综合征发生率61.4%,NPI-apathy与淡漠综合征诊断标准相关系数为0.617。淡漠程度与认知功能呈负相关,与抑郁障碍无显著相关性,与陪护负担相关性高于抑郁及认知功能。AES-C和LARS-I标准效度较好。进一步分析淡漠综合征各维度表现,目的性认知活动减少或缺失发生率最高。结论:淡漠综合征在AD患者中较常见,影响认知功能和陪护负担。NPI-apathy、AES-C和LARS-I量表具有较好的标准效度。
出处 《人民军医》 2011年第S1期46-49,共4页 People's Military Surgeon
基金 上海市科学技术委员会课题资助项目(08411950700 08411950800)
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