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DNA甲基化与胰岛素抵抗的研究进展 被引量：2

Research Pogress of DNA Methylation and Insulin Resistance
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摘要 DNA甲基化属于表观遗传学之一,研究发现DNA甲基化可导致胰岛素抵抗(insulin resistance,IR),而IR是2型糖尿病发生的始动因素。因此对DNA甲基化的研究可加深对IR的认识,为防治2型糖尿病及其并发症提供重要的科学依据。 DNA甲基化属于表观遗传学之一,研究发现DNA甲基化可导致胰岛素抵抗(insulin resistance,IR),而IR是2型糖尿病发生的始动因素。因此对DNA甲基化的研究可加深对IR的认识,为防治2型糖尿病及其并发症提供重要的科学依据。
作者 张玲玲 胡蕴 张日东 陈颖越 冯田田 毛晓明
机构地区 南京医科大学附属南京第一医院内分泌科
出处 《现代生物医学进展》 CAS 2011年第S2期5156-5158,共3页 Progress in Modern Biomedicine
基金 南京市科技局项目(200901076)
关键词 DNA甲基化 IR 表观遗传学 2型糖尿病 DNA methylation Insulin resistance Epigenetics Type2 diabetics
分类号 Q64 [生物学—生物物理学]
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参考文献31

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二级参考文献21

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共引文献16

同被引文献74

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现代生物医学进展
2011年 第S2期

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