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Microarray analysis of gene expression profiles in the bovine mammary gland during lactation 被引量:6

Microarray analysis of gene expression profiles in the bovine mammary gland during lactation
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摘要 Mammary glands undergo functional and metabolic changes during virgin,lactation and dry periods.A total of 122 genes were identified as differentially expressed,including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods.Gene ontology analysis showed the functional classification of the up-regulated genes in lactation,including transport,biosynthetic process,signal transduction,catalytic activity,immune system process,cell death,and positive regulation of the developmental process.Microarray data clarified molecular events in bovine mammary gland lactation. Mammary glands undergo functional and metabolic changes during virgin,lactation and dry periods.A total of 122 genes were identified as differentially expressed,including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods.Gene ontology analysis showed the functional classification of the up-regulated genes in lactation,including transport,biosynthetic process,signal transduction,catalytic activity,immune system process,cell death,and positive regulation of the developmental process.Microarray data clarified molecular events in bovine mammary gland lactation.
出处 《Science China(Life Sciences)》 SCIE CAS 2010年第2期248-256,共9页 中国科学(生命科学英文版)
基金 supported by the National High Technology Research and Development Program of China (Grant No. 2006AA10Z1A4) the Innovation Team of the Northeast Agricultural University (Grant No. LXT005-1-1)
关键词 MAMMARY GLAND microarray LACTATION GENOMICS gene expression profile mammary gland microarray lactation genomics gene expression profile
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