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Sweet综合征69例临床分析 被引量:5

Clinical analysis of 69 cases with Sweet's syndrome
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摘要 目的探讨Sweet综合征的临床及病理特征,以进一步认识本病并为其诊断和治疗提供参考。方法收集本院69例诊断为Sweet综合征患者的一般资料、皮疹情况、实验室检查及组织病理检查情况,用SPSS11.5统计软件分析处理数据。结果 69例患者男女比例为1.16:1,41~60岁最多见。20例有实验室指标,白细胞升高9例(45.0%)。69例患者皮损组织病理均表现为真皮内中性粒细胞浸润,2例(2.9%)患者表皮内有中性粒细胞浸润,6例(8.7%)患者皮下组织有中性粒细胞浸润,69例患者均无白细胞碎裂性血管炎表现。结论 69例Sweet综合征男女发病率基本一致,其皮损中中性粒细胞不仅浸润真皮层,还可累及表皮及皮下组织。 目的探讨Sweet综合征的临床及病理特征,以进一步认识本病并为其诊断和治疗提供参考。方法收集本院69例诊断为Sweet综合征患者的一般资料、皮疹情况、实验室检查及组织病理检查情况,用SPSS11.5统计软件分析处理数据。结果 69例患者男女比例为1.16:1,41~60岁最多见。20例有实验室指标,白细胞升高9例(45.0%)。69例患者皮损组织病理均表现为真皮内中性粒细胞浸润,2例(2.9%)患者表皮内有中性粒细胞浸润,6例(8.7%)患者皮下组织有中性粒细胞浸润,69例患者均无白细胞碎裂性血管炎表现。结论 69例Sweet综合征男女发病率基本一致,其皮损中中性粒细胞不仅浸润真皮层,还可累及表皮及皮下组织。
出处 《实用皮肤病学杂志》 2010年第2期79-81,共3页 Journal of Practical Dermatology
关键词 SWEET综合征 临床分析 Sweet’s syndrome Clinical analysis
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参考文献9

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同被引文献41

  • 1徐宏慧,肖汀,高兴华,何春涤,耿龙,陈洪铎.Sweet综合征42例分析[J].中国医科大学学报,2009,38(4):315-316. 被引量:2
  • 2张之南,沈悌.血液病诊断及疗效标准.3版.北京:科学出版社,2008:220-227.
  • 3Cohen PR, Kurzrock R. Sweet's syndrome revisited: a review of disease concepts. Int J Dermatol,2003 ,42 :761-778.
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  • 6Bourke JF, Keohane S, Long CC, et al. Sweet's syndrome and malignancy in the U.K. Br J Dermatol, 1997, 137:609-613.
  • 7Cohen PR, Kurzrock R. Sweet's syndrome and malignancy. Am J Med, 1987, 82 : 1220-1226.
  • 8Giasuddin AS, El-Orfi AH, Ziu MM, et al. Sweet's syndrome:is the pathogenesis mediated by helper T cell type 1 cytokines? J Am Acad Dermatol, 1998, 39:940-943.
  • 9Bourke JF, Jones JL, Fletcher A, et al. An immunohistochemical study of the dermal infiltrate and epidemlal staining for interleukins 1 in 12 cases of Sweet's syndrome. Br J Dermatol, 1996, 134:705-709.
  • 10Reuss-Borst MA, Pawelec G, Saal JG, et al. Sweet's syndrome associated with myeIodysplasia: possible role of cytokines in the pathogenesis of the disease. Br J Haematol, 1993, 84 (2) :356- 358.

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