戊二醛对壳聚糖-聚醚水凝胶溶胀动力学的影响

Effect of glutaraldehyde on swelling kinetics of chitosan-polyether hydrogel

以壳聚糖和聚醚为原料、戊二醛为交联剂合成了壳聚糖-聚醚水凝胶。研究了壳聚糖-聚醚水凝胶溶胀机理,探讨了戊二醛浓度对该水凝胶的溶胀度、溶胀速率和溶胀动力学的影响。结果表明,戊二醛浓度不仅是影响水凝胶溶胀度的主要因素,随着戊二醛浓度的增大,壳聚糖-聚醚水凝胶的溶胀度逐渐减小,而且影响其溶胀动力学类型,当戊二醛浓度为0.107mol·L-1,该水凝胶的溶胀过程属于Fickian类型,当戊二醛浓度为0.320、0.533mol·L-1,其溶胀过程属于non-Fickian类型。

Chitosan-polyether hydrogels were prepared with chitosan and polyether using glutaraldehyde as crosslinker.The swelling mechanism of chitosan-polyether hydrogel was studied,the concentration of glutaraldehyde affecting swelling ratio,swelling rate and swelling kinetics of this hydrogel were researched.The result showed that the concentration of glutaraldehyde was not only the main factor affecting the swelling ratio,which reduced when the concentration of glutaraldehyde increased,but also a factor affecting its dynamic swelling behavior,which fitted with Fickian model when the concentration of glutaraldehyde was 0.107 mol·L-1 while non-Fickian model when it was 0.320 mol·L-1 and 0.533 mol·L-1 respectively.