Crystallization and Preliminary Crystallographic Analysis of Histone Demethylase PHF8

Crystallization and Preliminary Crystallographic Analysis of Histone Demethylase PHF8

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摘要 The reversible process of histone methylation and demethylation plays important roles of epigenetic regulation1. For example, Truncating mutations in human PHF8 gene

作者 Lin Yu, Yang Wang, Zhongzhou Chen State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China

出处《生物物理学报》 CAS CSCD 北大核心 2009年第S1期320-321,共2页 Acta Biophysica Sinica

基金 supported by the Scientific Research Starting Foundation for Returned Overseas Chinese Scholars, Ministry of Education ,China National Natural Science Foundation of China (30870494) New Century Excellent Talents in University (NCET-07-0808) and China agricultural university

关键词 HISTONE DEMETHYLASE PHF8 Structure Protein CRYSTALLOGRAPHY Histone Demethylase, PHF8, Structure, Protein Crystallography

分类号 Q51 [生物学—生物化学]

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参考文献3

1Zhang,Y. et al. Genes and Development . 2001
2Laumonnier,F et al. Journal of Medical Genetics . 2005
3Koivisto A M et al. Clinical Genetics . 2007

1Tamaki Suganuma Jerry L Workman.Features of the PHF8/KIAA1718 histone demethylase[J].Cell Research,2010,20(8):861-862. 被引量：1
2Xiaoqiang Guo,Zha ntao Tian,Xuliang Wang,Shuhong Pan,Weiren Huang,Yongqing Shen,Yaoting Gui,Xianglin Duan,Zhiming Cai.Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2α[J].Acta Biochimica et Biophysica Sinica,2015,47(2):106-113. 被引量：6
3Jihui Qiu,Guang Shi,Yuanhui Jia,Jing Li,Meng Wu,Jiwen Li,Shuo Dong,Jiemin Wong.The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation[J].Cell Research,2010,20(8):908-918. 被引量：16
4Hanqing Lin,Yiqin Wang,Yanru Wang,Feng Tian,Pu Pu,Yi Yu,Hailei Mao,Ying Yang,Ping Wang,Lulu Hu,Yan Lin,Yi Liu,Yanhui Xu,Charlie Degui Chen.Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans[J].Cell Research,2010,20(8):899-907. 被引量：2
5Yan Zhang,Huirong Yang,Xue Guo,Naiyan Rong,Yujiao Song,Youwei Xu,Wenxian Lan,Xu Zhang,Maili Liu,Yanhui Xu,Chunyang Cao.The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B[J].Protein & Cell,2014,5(11):837-850. 被引量：3
6Falong Lu,Xia Cui,Shuaibin, Zhang,Chunyan Liu,Xiaofeng Cao.JMJ14 is an H3K4 demethylase regulating flowering time in Arabidopsis[J].Cell Research,2010,20(3):387-390. 被引量：14
7金雷,张林,王大成,Jan Markussen.Crystallization and preliminary crystallographic analysis of [A21Ser-B27Arg-B30Thr-NH_2]-human insulin[J].Chinese Science Bulletin,1995,40(11):949-952.
8LAN Fei1 & SHI Yang 2 1 Department of Biology, Constellation Pharmaceuticals, 148 Sidney Street, Cambridge, MA 02139, USA 2 Department of Pathology, Harvard Medical School, 77 Ave Louise Pasteur, Boston MA, 02115, USA.Epigenetic regulation: methylation of histone and non-histone proteins[J].Science China(Life Sciences),2009,52(4):311-322. 被引量：27
9Bo Zhou,Xiaonan Yang,Jianhao Jiang,Yubing Wang,Minghui Li,Muwang Li,Xuexia Miao,Yongping Huang.Silkworm （Bombyx mori） BmLid is a histone lysine demethylase with a broader specificity than its homolog in Drosophila and mammals[J].Cell Research,2010,20(9):1079-1082.
10Lin Yu,Yang wang,Shuo Huang,Jianjun Wang,Zengqin Deng,Qi Zhang,Wei Wu,Xingliang Zhang,Zhao Liu,Weimin Gong,Zhongzhou Chen.Structural insights into a novel histone demethylase PHF8[J].Cell Research,2010,20(2):166-173. 被引量：11

生物物理学报

2009年第S1期

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Crystallization and Preliminary Crystallographic Analysis of Histone Demethylase PHF8

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