Molecular dynamics simulations investigation of Neocarzinostatin Chromophore releasing pathways from the Holo-NCS protein
Molecular dynamics simulations investigation of Neocarzinostatin Chromophore releasing pathways from the Holo-NCS protein
摘要
The enediyne ring chromophore with strong DNA cleavage activity of neocarzinostatin is labile and therefore stabilization by forming the complex (carrying protein + chromophore:
作者
Xi Zhao1, Song Wang1, Xue-feng Gao2, Xu-ri Huang1, Chia-chung Sun1 1 State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130023, People’s Republic of China 2 College of L ife Science,Jilin University, Changchun 130023, People’s Republic of China
出处
《生物物理学报》
CAS
CSCD
北大核心
2009年第S1期377-377,共1页
Acta Biophysica Sinica
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