糖尿病患者冠状动脉斑块MSCT表现的临床研究

Clinical study on MSCT features of coronary plaque in DM patients

目的探讨糖尿病患者冠状动脉斑块的MSCT影像学特点,以及hsCRP在预测斑块稳定性中的作用。方法2008年6月—2008年11月因不稳定心绞痛行CTA检查的254例患者,按照有无糖尿病分为2组,检测生化指标和hsCRP,比较CTA影像学上冠脉病变情况和钙化特点。结果糖尿病组血浆hsCRP水平[(4.79±2.57)mg/L]高于非糖尿病组[(2.18±1.36)mg/L],差异有统计学意义(P<0.05)。糖尿病组三支血管病变比率为34.9%,钙化病变比率为64.2%,糖尿病组二者比率分别为14.5%和35.9%,差异有统计学意义(均P<0.05)。结论糖尿病组患者CTA影像较非糖尿病组患者更弥漫,钙化更明显,血浆炎症介质水平hsCRP升高。

Objective To investigate the CTA features of coronary plaque in DM patients and the relation between hsCRP and CTA images.Methods Two hundred and fifty-four unstable angina patients underwent CTA examination were analyzed.They were divided into 2 groups according to diabetic mellitus.Results The hsCRP in DM were higher than the non DM,([4.79±2.57] mg/L vs [2.18±1.36] mg/L,P<0.05).There were more 3-vessle lesions(34.9% vs 14.5%)and calcification coronary lesions(64.2% vs 35.9%)in DM group than non DM group(P<0.05).Conclusion The coronary lesion of CTA in DM patients is more serious,calcified and vulnerable than patients without DM.