针刺中渚、外关的脑功能性磁共振成像研究

Study of Acupuncture Zhongzhu(SJ3) and Waiguan(SJ5) by Functional MRI(fMRI)

目的研究针刺中渚穴、外关穴脑功能变化的规律和脑激活区的定位信息。为针灸治疗的中枢机制提供实验依据。方法利用fMRI-BOLD技术,获取8位健康志愿者的中渚穴和外关穴在行针状态下的脑功能变化图像。利用AFNI软件分析针刺中渚穴和外关穴时脑功能变化的规律。结果针刺左侧中渚穴和外关穴主要引起扣带回、颞叶、小脑、枕叶等的激活。结论针刺的镇痛效果可能是通过多个脑功能区的相互作用而产生的。

Objective To observe the distribution of the activated cerebral regions after acupuncture stimulation of Zhongzhu(SJ3) and Waiguan(SJ5) by functional magnetic resonance imaging(fMRI) technique.Methods A total of 8 cases of volunteer healthy subjects were recruited for this study.Before and during manipulation of the needle,cerebral images were sampled separately by fMRI scanner and analyzed by AFNI software.Results During manipulation of the needle inserted in the unilateral Zhongzhu(SJ3) and Wauguan(SJ5),the highly-activated cerebral structures were cingulated gyrus,temporal gyrus,cerebellum,occipital gyrus,etc.Conclusion The effect of acupuncture analgesia was probably produces by the interaction of multiple brain structures of functional connectivity rather than through the activation of a single brain region.